Pascal Jonkheijm was born in Vogelwaarde (Netherlands) on June 12th, 1978. He attended the Zeldenrust-Steelant College in Terneuzen (Netherlands) where he obtained his VWO (pre-university education) degree. In 1996 he started to study Chemical Engineering and Chemistry at the Eindhoven University of Technology (Netherlands). He graduated in August 2001 in the laboratory of Macromolecular and Organic Chemistry and in June 2005, he obtained his Ph.D. degree (cum laude, highest grade possible) in the same group with Prof. Dr. E. W. Meijer and Dr. A. P. H. J. Schenning as his advisors. During these years his research interest have been in macromolecular engineering of pi-conjugated oligomers through supramolecular interactions into nanoscopic objects. Part of his Ph.D. work was performed at the University of Leuven (Belgium) in collaboration with Prof. Dr. F. DeSchryver and Prof. Dr. Steven DeFeyter. His thesis was awarded with the Houwink Award (Macromolecules Research Award, 2005). After that, he moved for a post-doctoral stay as an Alexander von Humboldt research fellow (2006-2007) to the Chemical Biology department of Prof. Dr. H. Waldmann at the Max-Planck Institute for molecular Physiology in Dortmund (Germany). His research interests included protein microarrays and surface microstructuring techniques. After receiving a NWO Vernieuwingsimpuls Veni Grant on a project called Molecular Nanoscale Cell Manipulation, he started in 2008 as an Assistant Professor in the Molecular Nanofabrication group of Prof. Dr. J. Huskens at the University of Twente and MESA+ Institute for Nanotechnology. Currently he is appointed as an Adjunct-Professor at the same University and heading the laboratory of Bioinspired Molecular Engineering. He has recently received a Starters Grant from the European Research Council, a Young Investigator Award from the Biomedical Materials Program and a VIDI Grant of the Chemical Council for Scientific Research of the Dutch Science Foundation. His research project is called “Engineering molecular interfaces to cells” and is on the crossroad between (supramolecular) chemistry and chemical biology and uses tools from nanotechnology.
Jonkheijm research group members
Gülistan Kocer was born in Silvan, Turkey on March 10th, 1988. She received her BSc degree in Chemical Engineering from the Middle East Technical University (METU), Ankara, Turkey in 2011. As a part of her undergraduate studies, in the fall semester of 2009, she attended the Technical University of Denmark within the scope of an ERASMUS exchange programme. In August 2013, she received her MSc degree in Biomedical Engineering (cum laude) at the Department of Tissue Regeneration, University of Twente (UT) where she investigated the genome wide regulation of gene expression in osteogenic cells in response to surface structural properties of calcium phosphate ceramics. The work was carried out in the group of Prof. Dr. Jan de Boer and co-supervised by Dr. Roman Truckenmülller and Dr. Pamela Habibovic. From October to December 2013, she worked at the same department under the supervision of Dr. P. Habibovic on a project involving topographical modification of polymer substrates for cell studies. Since December 2013, she is a PhD candidate in the Molecular Nanofabrication group under the supervision of Prof. Dr. Ir. Pascal Jonkheijm. The aim of her project is to manipulate and investigate cellular behaviour using dynamic/stimuli responsive biomolecular functionalities on lipid bilayers.
Mark Verheijden was born in Oosterhout, The Netherlands, on February the 2nd 1989. He studied Chemical Engineering at the University of Twente. His bachelor assignment was performed at the University of Aberdeen with the topic “ESR investigation of TiO2 nanoparticles for photocatalytic applications”. His internship was performed at IBM (San Jose, USA) on “block copolymer coated paramagnetic nanoparticles for drug delivery”. He received his master degree (cum laude) at the University of Twente in October 2013. The topic of the master project was “Designing reversible cell interactions using supramolecular host-guest chemistry via strain promoted click chemistry on cell surfaces functionalized by metabolic labeling”
As of February 2014, he is a Ph.D. candidate under supervision of Pascal Jonkheijm, studying cell-surface interfaces. The aim of the research is to design surfaces that can selectively and dynamically interact with cells in order both study and gain control over these cell-surface interactions.
Maike Wiemann was born in Moers, Germany on November 8th, 1988. She studied chemistry at the Ruhr-University Bochum, where she received her bachelor degree in September 2011 and also her master degree in October 2013. During her master thesis she worked on the “Synthesis and Characterization of EGFR Targeting Peptides GE11(2R) and Organometallic GE11(2R)bioconjugates”.
In May 2014 she started her PhD program in the Molecular Nanofabrication group under the supervision of Prof. Dr. Pascal Jonkheijm. The aim of her project is the development of responsive bioactive interfaces to cells in order to study and manipulate cellular processes.
Sara Longo was born on October 30th 1989 in San Dona’ di Piave, Italy. Here, she attended the “Liceo Classico Montale” as pre-university education school. She pursued her Bachelor’s degree in Chemistry (summa cum laude) in June 2011 at Ca’ Foscari University of Venice. At the same university, she gained her Master’s degree in Science and Technologies of Bio and Nanomaterials (summa cum laude), in March 2016 (Detection of different isotypes of anti-tissue transglutaminase by nanoelectrode ensemble biosensors for celiac disease diagnosis). Since August 2016, she is a PhD candidate in the Molecular Nanofabrication (MNF) group under the supervision of Prof. Dr. Ir. Jurriaan Huskens and Prof. Dr. Ir. Pascal Jonkheijm. The goal of her project is studying multivalent interactions at interfaces with biomolecular/biological systems, with the aim to apply them in the biomedical field, such as for developing bio-sensing devices.
Nicole Zeijen was born the 13th of October 1984 in Oldenzaal, the Netherlands. She obtained her Master degree in Biomedical Sciences at the Radboud University Nijmegen in 2008 under supervision of prof. dr. Aldert Piersma and it was aimed at the characterization of proliferation and differentiation of embryonic stem cells differentiating to cardiomyocytes. For over a year she worked at the University of Twente as a researcher in the project of circulating tumour cells, after which she returned to academia to receive a Bachelor degree in Chemistry at Saxion University of Applied Sciences in 2013. Her thesis concerned unravelling the working mechanism of the anticancer agent 3-bromopyruvate in the field of Nanotechnology. During her 2 year studies, she was taken on as a lecturer in the field of Toxicology at Saxion, where she is still employed part time in Forensic Science. Since the 1st of September 2016, she is granted a scholarship from Saxion to work on her PhD under the supervision of prof. dr. ir. Pascal Jonkheijm. Her project includes the differentiation of mesenchymal stem cells when manipulated by biomolecular stimuli on lipid bilayers, co-supervised by Dr. Andries van der Meer.
Liulin Yang was born in China in 1983. He majored on material science and technology at the Xiamen University (China), where he received his bachelor degree in July 2004. Then he started his PhD project under the supervisor of Prof. Yanming Dong at the Xiamen University (China). He received his Ph.D. degree in 2011. The aim of his project was to develop a series of carbohydrate-based liquid crystalline dendrimers.
From May 2012 to May 2015, he worked as a post doc in the group of Prof. Xi Zhang at the Tsinghua University. During this period, he and co-workers developed new methods for controlled synthesis and characterization of supramolecular polymers.
Since May 2015, he is a post doc in the BNT group of Prof. Jeroen J.L.M. Cornelissen and MnF groups of Prof. Pascal Jonkheijm. The aim of the project is to develop hybrid (gel-like) materials based on the combination of plant viruses and supramolecular chemistry.
Inês Cunha Albino (BME)
Ester de Boer (BME)
Aukie Hooglugt (BME)
Dr. E. Cavatorta (now at Friesland Campina)
Dr. J. Brinkmann
Dr. B. Schmidt
Dr. Shrikrishnan Sankaran (now at Leibniz Institute for New Materials/Germany)
Dr. Tushar Satav (now at Pepscan/NL)
Dr. Jasper van Weerd (now at LipoCoat B.V.)
Dr. Arántzazu González Campo (now at D. Amabilino/ICMAB)
Dr. Lanti Yang (now at Sabic)
Dr. Dorothee Wasserberg (now at L. Terstappen/UT)
Dr. Alberto Gomez-Casado (now at Anton Paar/Austria)
Dr. Francesca Scaramuzzo (now at Padova)
Dr. Erhan Bat (now at Ankara University)
Dr. Pieter Moonen (now at BASF)
Dr. Q. An (now at Univeristy of Geosciences/Beijing)
Dr. Jordi Cabanas Danés (now at G. Wuite/Amolf)
Dr. Nicole Georgi
Dr. Wies van Roosmalen (now at Dutch Cancer Fund)
Dr. Jens Voskuhl (now at Uni Duesseldorf)
Eveline van Kampen (now at Leiden University)
Mark de Ruiter, MSc.
Nora Weineisen, MSc.
Laura Belen Merino Gamo (erasmus student)
Aylin Oymaci (intern from “Saxion hogeschool”)
Eiko Westerbeek (bachelor student Utwente)
Lucas Gaalman (bachelor student Utwente)
Emanuela Cavatorta (Carre 4.063; +31 53 489 2933; firstname.lastname@example.org) was born in Parma (Italy) on January 7th, 1986. In the same city, she attended the Liceo Classico Romagnosi, where she obtained her pre-university education degree. In 2007 she got her bachelor degree in Food Science at the University of Parma, presenting a thesis about ”Allergenic protein extraction from biological matrices”, based on a four months project at the Molecular Biology Department, under the supervision of Prof. Claudia Folli. Two years later she got her bachelor degree in Chemistry with a thesis about ”Ionic liquids and their use as heterogenic catalysts in Knövenagel reaction”, after working five months at the Organic Chemistry Department in Prof. Franca Bigi’s group. During her master course, she spent six months in the Molecular NanoFabrication Group at the University of Twente as an exchange student, working on her master project. In April 2012 she defended her master thesis entitled ”Surface-immobilized Peptide-Nucleic Acids (PNAs) for sensing applications“, under the supervision of Prof Roberto Corradini of the University of Parma.
Since May 2012, she works as a PhD in the group of Pascal Jonkheijm. The aim of her project is to design and study methods to introduce chemical functional groups to cell surface.
Bettina Schmidt (Carre 4.236; +31 53 489 2933; email@example.com) studied Chemistry at the Technische Universität Dresden, Germany, where she obtained her bachelor degree in 2009. During her master course at the same university she spent four months as an Erasmus student dealing with the design and synthesis of metal-organic frameworks MOFs for separative and sensing applications under the supervision of Prof. Dr. Martin Schröder and Dr. Rafel Cabot Mesquida at the University of Nottingham, United Kingdom. In 2011 she graduated from the university in Dresden working on the synthesis and characterisation of flavonoid-based ligands and the study of their transition metal complexes under the direction of Prof. Dr. Karsten Gloe.
Since October 2011 she is a PhD candidate in the group of Pascal Jonkheijm. The aim of her project is the development of porphyrin-based supramolecular assemblies and their functionalization with biomolecules for targeting studies under physiological conditions.
Jenny Brinkmann (Carre 4.052; +31 53 489 2933; firstname.lastname@example.org) received her B.Sc. in Biomedical Engineering in 2009, a program offered jointly by The Technical University of Denmark and The Faculty of Health Sciences at Copenhagen University. In June 2011 she received her M.Sc. in Biomedical Engineering, specializing in Molecular Bioengineering, at The Federal Swiss Institute of Technology (ETH) Zurich. In her master project she worked on the characterization of osteoclasts in response to changes in surface topography. The project was carried out at the Laboratory for biologically oriented materials (ETH Zurich, Switzerland) under the supervision of Thomas Hefti and PD Dr. Heike Hall. In October 2011 she joined the groups of Dr. P. Jonkheijm and Dr. Jan de Boer (Tissue Regeneration) as a Ph.D. candidate at the University of Twente. The aim of her project is to use pattered substrates of peptides/proteins to investigate and control endothelial cell migration.
Shrikrishnan Sankaran (Carre 4.052; +31 53 489 2933; email@example.com) was born in Bangalore, India, on 7th January 1988. He pursued a five year dual degree program consisting of B.E.(Hons) in Electronics and Instrumentation and M.Sc.(Hons) in Biological Sciences at Birla Institute of Technology and Science (BITS), Pilani from 2006 to 2011. His final year Masters Thesis was done at the Raman Research Institute, Bangalore under Prof.V.Lakshminarayanan on "Electrochemical Analysis of Biomolecular Interactions".
Since October 2011, he is a PhD candidate under the supervision of Dr.Pascal Jonkheijm at the University of Twente. His project involves developing dynamic bacterial systems using supramolecular interactions.
Tushar Satav (Carre 4.236; +31 53 489 2933; firstname.lastname@example.org) was born in Amravati, India on March 24th 1987. He received a M.S. (Pharm.) degree in medicinal chemistry from National Institute of Pharmaceutical Education and Research (NIPER), India under the supervision of Prof. Dr. Asit K. Chakraborti (FRSC) in July 2011. Towards the fulfillment of M.S. (Pharm.) degree he has submitted a thesis entitled “New scaffolds for selective COX-2 inhibition: Design, synthesis and biological evaluation of novel compounds”.
Since August 2011, he is a PhD under the supervision of Pascal Jonkheijm at the University of Twente, where he studies multivalent ligand synthesis and their biological evaluation.
Jasper van Weerd (CR 4236; +31 53 489 2937; email@example.com) was born in Almelo (the Netherlands) on the 24th of October 1985. From 2003 till 2007 he studied ‘Biology and Medical laboratory research’ at the Saxion University of Applied Sciences (Enschede, the Netherlands). In July 2007 he obtained his ‘Bachelor in applied science’ degree. His bachelor project was concerned with the development of a rapid DNA detection method for airborne biological agents for air quality/sampling purposes. This work was carried out at ZebraBioscience B.V. (Enschede, the Netherlands) under supervision of Dr. R.P. van Weeghel (CEO). In September 2007 he started a Biomedical Engineering master during which he specialized in ‘Molecular, Cellular and Tissue Engineering’. In October 2010 he received his master’s degree at the University of Twente. During his 9-month master project he worked on the development of a non-covalent, bio-active biomaterial coating for enhanced tissue repair. Work was carried out at the ‘Cellular Architecture and Dynamics group (Utrecht University; Utrecht, the Netherlands), ‘Polymer chemistry and BioMaterials group’ and the ‘Tissue Regeneration department’ (University of Twente, Enschede, the Netherlands). During this project he was supervised by Prof. Dr. C.A. van Blitterswijk and Dr. H.B.J. Karperien of the Tissue Regeneration department, Prof. Dr. C.T. Verrips and Dr. M. El. Khattabi of the Cellular Architecture and Dynamics group.
Also, alongside his master study he was employed by ZebraBioscience BV (2008 till 2010) as a part-time researcher on the FP6 EU-project HIBISCUS (Hybrid Integrated Bio-Sensor Created by Ultrafast Laser Sources). Here, he worked on various topics ranging from microfluidics, optics to genetic engineering to design a µCE platform for high resolution, multiplexed DNA separation. This work was carried out at/with: ZebraBioscience BV, Micronit BV, Lionix BV, Integrated Optical Microsystems group University of Twente and the Politechnico de Milano, Italy.
Since October 2010 he is a PhD candidate under supervision of Dr. Pascal Jonkheijm and Prof. Dr. Marcel Karperien at the University of Twente. The aim of his project is to develop novel interfaces to living cells which in turn can be used in cell studies and tissue regenerative studies.
Tom Steentjes (Carre 4.236; +31 53 489 2933; firstname.lastname@example.org) was born on the 18th of October 1982 in Doetinchem. He studied Chemical Engineering at the University of Twente in Enschede and obtained his bachelor degree in 2007. In 2010 he graduated in the Molecular Nanofabrication group under the supervision of Dr. Pascal Jonkheijm with a thesis called “Light-induced immobilization of a novel perylene bisimide by the thiol-ene click reaction”.
Since January 2010 he is a PhD candidate in the Molecular Nanofabrication group under the supervision of Prof. Dr. Jurriaan Huskens and Dr. Pascal Jonkheijm. The aim of his project is the surface modification for electrochemically amplified biosensing.
Nicole Georgi received her Master of Science degree from the Dresden University of Technology after a 9 months research visit to the Regenerative Medicine Lab of Prof. Dr. Dietmar Hutmacher (Brisbane, Australia). She performed her PhD research at the department of Developmental BioEngineering at the University of Twente under the supervision of Prof. Dr. Marcel Kaperien. Her work during her PhD focused on the optimization of the use of MSCs in cartilage tissue engineering as well as their use in co-culture approaches. By using optimized culture conditions the differentiation potential of MSCs was improved and furthermore their role in co-culture models with chondrocytes was investigated. Her research led to three successful publications as well as a personal scholarship of the German Academic Exchange Service for her research visit to the Cartilage Regeneration Laboratory (CRL) of Travis Klein (Brisbane, Australia) from September 2011-December 2011. In February 2013 she joined the group of dr. Pascal Jonkheijm (MESA+, University of Twente) as a postdoctoral researcher. The aim of her project is to deliver RNA to cells exploiting a light and/or an electro-active responsive supramolecular system.
Wies van Roosmalen obtained her Master Degree in Biopharmaceutical Sciences in 2007 at Leiden University. As part of her master program, she did an internship at the division of Toxicology (LACDR, Leiden University) under supervision of dr. Martine van Miltenburg and prof. dr. Bob van de Water, aiming to develop methodologies to study the role of Focal Adhesion Kinase in breast cancer progression. In addition, she did an internship at the Department of Anatomy and Structural Biology (AECOM, New York) under supervision of dr. Jacco van Rheenen and prof. dr. John Condeelis. The aim of this project was to study the role of PIP2 hydrolysis in activation of cofilin in metastatic breast cancer cells.
In 2008, she rejoined the division of Toxicology (LACDR, Leiden University) as a PhD student under supervision of prof. dr. Bob van de Water. The aim of her project was to identify novel candidate metastasis genes that could serve as putative drug targets for breast cancer treatment and/or serve as biomarkers that predict poor disease outcome. As part of her project, she worked in the group of prof. dr. Benjamin Geiger (WIS, Israel) as a visiting scientist to collaborate on a high-throughput tumor cell migration screen.
In October 2012 she joined the group of dr. Pascal Jonkheijm (MESA+, University of Twente) as a postdoctoral researcher. The aim of her project is to combine supramolecular chemistry with cell biology to manipulate endothelial cell migration and improve vascular stents.
Jens Voskuhl was born in Papenburg (Germany) on October 12th 1982. He started to study chemistry in Münster in 2002 and obtained his diploma in organic chemistry in 2008 in the workgroup of Prof. Dr. Bart Jan Ravoo. His thesis was entitled “Electrostatic and enantioselective recognition of cyclodextrin vesicles”. In the same year he started his PhD project in the same group and graduated “summa cum laude” in 2011. His topic was based on supramolecular chemistry involving molecular recognition in aqueous media based on cyclodextrin host guest complexes. In august 2011 he started a Postdoc project at the University of Leiden (The Netherlands) together with Dr. Alexander Kros. His topic involved the specific interaction of coiled coil binding motifs, which are able to induce fusion processes between lipsomes and membranes.
In march 2013, he started as a Postdoctoral research fellow in the Molecular NanoFabriaction group under the supervision of Dr. Pascal Jonheijm. His topic is based on specific molecular recognition of photo-switchable guest molecules on cyclodextrin monolayers as well as the immobilization of liposomes and vesicles on these surfaces.